ImmunArray Enters Partnership with Kindstar Global

ImmunArray, a privately held molecular device company dedicated to the development of novel, blood-based in vitro diagnostic tests, and Kindstar Global Co., Ltd., a specialty clinical testing company based in Wuhan, China with locations throughout mainland China, have forged a partnership involving shared clinical studies and the launch of ImmunArray’s lupus rule-out test in China as the initial product offering.

The companies will undertake joint clinical testing of up to 500 serum samples from Chinese
patients who are healthy as well as those with symptoms consistent with systemic lupus
erythematosus (SLE) or lupus. The study will support the clinical implementation of
ImmunArray’s SLE-Key Rule-Out® test, which was introduced in U.S. markets in 2016. Previous
clinical trials have found the test delivers a differential diagnosis with >90% sensitivity and
>70% specificity.

ImmunArray will provide training to Kindstar staff in ImmunArray’s Richmond facility and onsite
in the first two labs in China. The detection platform on which the ImmunArray manufactured
iChip® test has been cleared by the CFDA which will facilitate the introduction of the first of the
tests planned for the market.

The diagnosis and treatment of lupus is not simply an American challenge but one that affects
populations around the world. The Chinese population has the second largest prevalence of
lupus in the world with over 1 million patients identified with lupus in that country today.
ImmunArray is working closely with AMPEL BioSolutions, co-founded by Drs. Peter Lipsky and
Amrie Grammer, with whom ImmunArray announced a Strategic Partnership on World Lupus
Day in May 2017. Dr. Lipsky has had the good fortune to provide training to some of the
leaders of the Chinese academic rheumatology community and maintains active collaborations
with many. He will be a co-chair of the Scientific Advisory Board with leading Chinese academic
rheumatologists, making recommendations to ImmunArray and Kindstar concerning their joint
venture.

“This partnership with Kindstar combines the resources of two innovative diagnostic
companies that are focused on finding solutions to the diagnosis of autoimmune diseases, and
we are extremely excited about the possibilities that this alliance can afford both parties,” said Donna
Edmonds, CEO of ImmunArray.

“The business relationship and expanded market opportunity this provides to Kindstar is an
important part of our strategy to be the premier specialty laboratory in China,” said Shiang
Huang, M.D., Kindstar founder and CEO. “We are focused on providing testing to a growing
number of specialists as they support patient care. This expanded product line for
rheumatologists is another demonstration of that commitment.”

As part of the agreement, Kindstar will acquire the exclusive rights to market ImmunArray’s
SLE-Key Rule-Out test in China. The launch of the product into the Chinese market is tentatively
set for November 2017 and will be formally announced at the internationally attended
American College of Rheumatology annual meeting in San Diego.

About ImmunArray
Founded in 2006 and co-located in Rehovot, Israel and Richmond, Va., ImmunArray’s novel blood-based
testing platform supports the diagnosis and management of complex acute and chronic immune and
neurodegenerative diseases. The company designs and analyzes sets of biomarkers known to be linked
to a particular condition and develops tests on platforms that are most appropriate to facilitate the
adoption of additional tests. The company’s first commercial test, the SLE-Key® Rule-Out Test, is used to
assist physicians in ruling out Systemic Lupus Erythematosus (SLE) or lupus as part of a differential
diagnosis. The company has a pipeline of products in development to support diagnosis and
management of other auto-immune and neurological diseases.

About Kindstar Co., Ltd.
Founded in 2003 and based in Wuhan, China, Kindstar Global Co., Ltd. provides specialty clinical testing
services throughout China. The company offers esoteric diagnostic testing and laboratory testing
services to Chinese hospitals, including tertiary care hospitals. The company has a long standing
partnership with the Mayo Clinic and has laboratory facilities in Beijing, Shanghai and Wuhan. It was
formerly known as Wuhan Kindstar Diagnostics Co., Ltd.

For further information please contact:
Kelsey Leavey (U.S)
The Hodges Partnership
804-788-1414
kleavey@hodgespart.com

AMPEL BioSolutions and ArcheMedX Form Partnership

AMPEL BioSolutions, a leading translational medicine and clinical operations company and ArcheMedX, a digital platform for effective online health care education and training programs, today announced a new collaboration to transform clinical trial recruitment and retention by enabling research sites to more effectively educate and continually engage clinical staff and patients.

The partnership will address the challenges with patient recruitment and retention for clinical trials by developing a new model for improving communication and education across study sites. By combining AMPEL’s extensive clinical expertise with the award-winning ArcheMedX e-learning and analytics platform, AMPEL and ArcheMedX will ensure that principal investigators, trial coordinators, clinical staff, and patients are well informed and continually engaged throughout the trial.

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Virginia Bio Welcomes New Members to its Board of Directors

Virginia Bio, the premier statewide non-profit association representing the life science industry in the Commonwealth of Virginia, has elected five new members to their Board of Directors for a term of three years. The election took place on December 8, 2016 at the Virginia Bio Annual Membership meeting in Richmond, Virginia.

The newly elected directors are: Rony Thomas, President & CEO, LifeNet Health; Thomas Frantz, Chairman Emeritus, Williams Mullen; Julie Idelkope, Vice President, US Government Relations, Pfizer; Amrie Grammer, COO & CSO, AMPEL BioSolutions; Ross Dunlap, President & CEO, Ceres Nanosciences; and Mickey Kim, Director, Biotech Partnering & Strategy, MedImmune.

Read more: http://www.businesswire.com/news/home/20161219006218/en

Data mining could lead to therapy advances

In the past 50 years, only one new therapy has been approved for the treatment of lupus.

Peter E. Lipsky, MD, Co-Founder and Chief Executive Officer of AMPEL BioSolutions, Charlottesville, VA, works to change that, and he will discuss his efforts during the Clinical Science symposium Mining Big Data for Drug Repurposing.

The symposium will take place from 11:00 am – 12:00 pm on Tuesday in room 146A and will demonstrate the potential role of genetics and data mining strategies in identifying new or repurposed therapeutic targets for systemic autoimmune rheumatic diseases.

Read more… http://www.acrdailynewslive.org/data-mining-could-lead-to-therapy-advances/

New Results Published Demonstrate Effectiveness of AMPEL’s Innovative System

New results published in the professional journal Lupus demonstrate the effectiveness of an innovative system developed to identify promising treatments for lupus among existing drugs approved for use in other diseases. Funded by the Lupus Research Alliance and the John and Marcia Goldman Foundation, the study used Big Data to confirm selection of potential treatments identified by analyzing data on over 1,000 drugs approved by the U.S. Food and Drug Administration and eliciting broad feedback via internet crowd-sourcing.

The LRxL-STAT (Lupus Treatment List-SLE Treatment Acceleration Trials) was initiated by the Lupus Research Alliance) with Drs. Peter Lipsky and Amrie Grammer of AMPEL BioSolutions to address the urgent need for safer, more effective lupus treatments.

Click here to read the full article.