Kadmon Corporation’s Lupus Treatment Candidate Designated Top Priority

The Kadmon Corporation’s Phase 2 oral drug, KD025, a potent, bio-available and highly selective inhibitor of ROCK2 (Rho-associated coiled-coiled kinase 2) that can be taken orally was designed as one of its priority candidates to treat lupus through the LRxL-STAT Lupus Drug Repositioning Initiative. The selection of the drug was presented at the annual American College of Rheumatology meeting in November by Amrie Grammer, Ph.D., and Peter Lipsky, M.D.

The LRxL-STAT Lupus Drug Repositioning Initiative is a joint effort of the Alliance for Lupus Research (ALR) and the Lupus Research Institute (LRI) to accelerate the identification of new treatments with high potential for treating lupus. In collaboration with AMPEL BioSolutions, 157 potential therapies were evaluated and ranked through the CoLT, or Combined Lupus Treatment, scoring system, including KD025.

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