Peer-Reviewed Journal Articles
Published in Internationally Recognized Peer-Reviewed Journals
Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and European ancestry
Molecular mechanisms governing the progression of nephritis in lupus prone mice and human lupus patients
Machine learning reveals distinct gene signature profiles in lesional and nonlesional regions of inflammatory skin diseases
Altered expression of genes controlling metabolism characterizes the tissue response to immune injury in lupus
The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus
Deconvoluting the heterogeneity of SLE: The contribution of ancestry
Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries
COVID-19 Patients Exhibit Unique Transcriptional Signatures Indicative of Disease Severity
Medelian Randomization and Pathway Analysis Demonstrate Shared Genetic Associations Between Systemic Lupus Erythematosus and Coronary Artery Disease
Transcriptomics data: pointing the way to subclassification and personalized medicine in systemic lupus erythematosus
Molecular endotypes of type 1 and type 2 SLE
AMPEL Genomic Platform (AGP®) Bioinformatic Tools and Machine Learning Analytics
Abnormalities in intron retention characterize patients with Systemic Lupus Erythematosus
Nature Sci. Rep. 13:5141, 2023.
https://www.nature.com/articles/s41598-023-31890-4
Anti-RNP antibodies are associated with the interferon gene signature but not decreased complement levels in SLE
Ann Rheum Dis, 2022.
http://dx.doi.org/10.1136/annrheumdis-2021-221662
Application of machine learning for patient classification and outcome prediction in RAIDS (Rheumatic Autoimmune Inflammatory Diseases)
Nature Reviews Rheumatology 17: 710, 2021.
https://www.nature.com/articles/s41584-021-00708-w (featured on printed cover and website landing page, December 2021).
Nucleic acid sensing and interferon-inducible pathways show differential methylation in MZ twins discordant for lupus and overexpression in independent lupus samples: Implications for pathogenic mechanism and drug targeting,
Genes 12: 1898, 2021.
https://www.mdpi.com/2073-4425/12/12/1898
Expression of human endogenous retroviruses in Systemic Lupus Erythematosus: multiomic integration with gene expression
Frontiers in Immunology 4:661437, 2021.
doi: 10.3389/fimmu.2021.661437.
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity
Nature Immunology 22:1107, 2021.
https://www.nature.com/articles/s41590-021-00993-3
Repositioning Drugs for Systemic Lupus Erythematosus
SLE: Basic, Applied and Clinical Aspects, pp. 641, 2020.
https://www.sciencedirect.com/science/article/pii/B9780128019177000668
Antagonizing miR-7 suppresses B cell hyperresponsiveness and inhibits lupus development.
J. Autoimmun. 109:102440, 2020.
https://www.sciencedirect.com/science/article/abs/pii/S0896841120300536.
Drug Repurposing to Improve the Treatment of Patients with Rheumatic Autoimmune Inflammatory Diseases (RAIDs)
Nature Reviews Rheumatology 16:32, 2020.
https://www.nature.com/articles/s41584-019-0337-0
Systems and methods for single-cell RNA-Seq data analysis
US202000090787A1.
Machine Learning Approaches to Predict Disease Activity from Gene Expression Data
Nature Scientific Reports 9:9617, 2019.
https://www.nature.com/articles/s41598-019-45989-0 https://www.jimmunol.org/content/early/2019/04/23/jimmunol.1801512
Genomic Identification of Low-Density Granulocytes and Analysis of their Role in the Pathogenesis of Systemic Lupus Erythematosus
J. Immunol. 202:3309, 2019.
https://www.jimmunol.org/content/202/11/3309
Identification and characterization of post-activated B cells in systemic autoimmune diseases
Frontiers in Immunology 10:2136, 2019.
https://www.frontiersin.org/articles/10.3389/fimmu.2019.02136
Identification of alterations in macrophage polarization associated with disease activity in systemic lupus erythematosus
PLoS One 13(12):e0208132, 2018.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478921/
Aberrant Expansion and Function of Follicular Helper T Cell Subsets in IgG4-Related Disease
Arthritis Rheumatol.70:1853, 2018
doi: 10.1002/art.40556. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220938/
Drug Repositioning Strategies for the Identification of Novel Therapies for Rheumatic Autoimmune Inflammatory Diseases
Rheum Dis Clin. 43:467-480, 2017.
https://pubmed.ncbi.nlm.nih.gov/28711146/
Drug Repositioning in SLE: Crowd-Sourcing, Literature-Mining and Big Data Analysis
Lupus 25:1150-1170, 2016.
https://pubmed.ncbi.nlm.nih.gov/27497259/
Repositioning Drugs for SLE
in SLE: Basic, Applied and Clinical Aspects, pp. 567-575, 2016.
https://www.sciencedirect.com/science/article/pii/B9780128019177000668
The Epigenetics of Autoimmunity & Immune Disorders
in The Epigenome and Developmental Origins of Adult Health and Disease, pp. 211-234, 2015.
A comprehensive approach to identify approved drugs and treatments for repositioning as therapies for systemic lupus erythematosus
Arthr. Res. Ther. 16: 51, 2014.
https://arthritis-research.biomedcentral.com/articles/10.1186/ar4667
Increased frequency of a unique spleen tyrosine kinase bright memory B cell population in systemic lupus erythematosus
Arthritis Rheumatol. 66:3424, 2014.
https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.38854
Lymphoablation including B cell depletion and autologous hematopoietic stem cell transplantation leads to long remissions in treatment- resistant Systemic Lupus Erythemstosus Patients
Arthritis and Rheum. 65: 1610, 2013.
Molecular Characterization of Circulating Plasma Cells in Patients with Active Systemic Lupus Erythematosus
PLoS One 10: e0044362, 2012.